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ErSO treatment ablates mutant ERα breast cancer cell line xenografts and a PDX mouse model
9 μM for Timoprazole
7(13): 16282–16296
Smiles: NC1=NC(N)=C(C#N)C(N[C@@H](C2CC2)C2=NC3=C(F)C=CC(Cl)=C3C(=O)N2C2=CN=CC=C2)=N1
as the pKa of the more acidic imide nitrogen of the pyrimidine ring is a value of 7
Enzalutamide carboxylic acid 407AAO inhibitor-1 ErSO treatment ablates mutant ERαEnzalutamide carboxylic acid (MDV3100 carboxylic acid) is an inactive metabolite of Enzalutamide (MDV3100). Enzalutamide is an androgen receptor (AR) antagonist. Product information CAS Number: 1242137 15 0 Molecular Weight: 451. 39 Formula: C20H13F4N3O3S Chemical Name: 4 {3 [4 cyano 3 (trifluoromethyl)phenyl] 5,5 dimethyl 4 oxo 2 sulfanylideneimidazolidin 1 yl} 2 fluorobenzoic acid Smiles:
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