![CJ-42794 Catalog No.:M20871-C 5-e]azepin-2-yl)amino)benzoic acid](https://cdn.shopify.com/s/files/1/0389/1897/9723/products/M20871_1635206878.gif?v=1635206879)
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5-e]azepin-2-yl)amino)benzoic acid
inhibits bacterial protein synthesis and bears a unique indole side ring system and regiospecific hydroxyl groups on the characteristic macrocyclic core
the MSN spine density in EVP4593-treated WT mice was 13
InChiKey: GFZHNFOGCMEYTA-UHFFFAOYSA-N
In this model
CJ-42794 Catalog No.:M20871-C 5-e]azepin-2-yl)amino)benzoic acidCJ 42794 is a selective prostaglandin E receptor subtype 4(EP4) antagonist, inhibits [3H] PGE2 binding to the human EP4 receptor with a mean pKi of 8. 5, a binding affinity that was at least 200 fold more selective for the human EP4 receptor than other human EP receptor subtypes (EP1, EP2, and EP3). IC50 value: 8. 5 (pKi ) Target: EP4in vitro: CJ 042794 competitively inhibits PGE2 evoked elevations of intracellular cAMP levels in HEK293 cells
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