One of the tricks of building a Modern sideboard is to include cards that do something relevant in a wide range of matchups, since there are simply too many decks to dedicate sideboard slots to each one individually, and the fact that Isolate hits a very diverse range of targets and is live against nearly every deck in the format could mean that it ends up as a sideboard staple
Many have asked for this to be banned in Commander since entire decks are built around breaking it in their decks with a storm count win like Tendrils of Agony after dropping all of those zero cost artifacts or Dark Ritual effects
Runner-Up : Meld From time to time, Magic needs to design things that makes players go, "Can they do that?" Yes, design needs a lot of workhorse mechanics that get the job done, but it also occasionally needs some splash
Sure, it's more limited than Enchantments like Mesa Enchantress above, but with three options, you have three deck types he can lead - Equipment, Auras and Enchantments are all in the top 15 archetypes
Overall, the chase cards from this set have retained value well