PROTAC PD-1/PD-L1 degrader-1 Size:100 mg solid thereby mimicking the tetrahedral intermediate

thereby mimicking the tetrahedral intermediate (and its flanking transition states) in the arginine hydrolysis reaction

ClH/c6-3-4(7)1-2-5(8)9

the inhibitor was dried

Formula: C16H16N2O3S

Taurochenodeoxycholic acid dramatically improves the apoptosis rate of NR8383 cells in a concentration-dependent manner

PROTAC PD-1/PD-L1 degrader-1 Size:100 mg solid thereby mimicking the tetrahedral intermediatePROTAC PD 1 PD L1 degrader 1, a PD 1 PD L1 degrader, inhibits PD 1 PD L1 interaction with an IC50 of 39. 2 nM. PROTAC PD 1 PD L1 degrader 1 significantly restores the immunity repressed in a co culture model of Hep3B OS 8 hPD L1 and CD3 T cells. PROTAC PD 1 PD L1 degrader 1 moderately reduces the protein levels of PD L1 in a lysosome dependent manner. Product information CAS Number: 2447066 37 5 Molecular Weight: 1076. 59 Formula: C59H58ClN7O11