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12-pentaen-9-yl]acetamido}ethoxy)ethoxy]ethoxy}acetamido)-3
C2HF3O2/c18-12-2-1-10(19)7-13(12)28-11-3-5-24(6-4-11)15-8-14(29-22-15)17-20-23-25(21-17)9-16(26)27
InChi: InChI=1S/C17H12N2O6S2
InChi: InChI=1S/C21H11NO5S/c23-11-4-6-13-17(8-11)26-18-9-12(24)5-7-14(18)21(13)15-2-1-3-16(22-10-28)19(15)20(25)27-21/h1-9
dual specificity threonine/tyrosine kinases often upregulated in various cancer cell types
Reversine Catalog No.:M10364-10 12-pentaen-9-yl]acetamido}ethoxy)ethoxy]ethoxy}acetamido)-3Reversine is a small molecule developed by the group of Peter G. Schultz, used for stem cell dedifferentiation. Reversine is also a novel Aurora kinases inhibitor that inhibits colony formation of human acute myeloid leukemia cells. Reversine inhibits the phosphorylation of histone H3, a direct downstream target of Aurora kinases. Similarly to the Aurora kinase inhibitor VX 680, reversine inhibited colony formation of leukemic cells from patients with