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P388/VCR and P815/VLB
Miltefosine is an orally- and topically-active alkyl-phosphocholine compound with potential antineoplastic activity
Smiles: OC1=CC=C(C=C1CO)C(O)CNCCCCCCOCCCCC1C=CC=CC=1
but only slightly more potent than CC-5013 at elevating IFN-γ levels
Solubility: DMSO : ≥ 38 mg/mL (61
FT011 Size:2mg solid P388/VCR and P815/VLBFT011 is an anti inflammatory and anti fibrotic agent that has been reported to attenuate organ damage in diabetic rats with cardiomyopathy and nephropathy. In diabetic rats, FT011 reduced retinal leukostasis, microglial density and mRNA levels of intercellular adhesion molecule 1 (ICAM 1). In Mller cells, FT011 reduced diabetes induced gliosis and vascular endothelial growth factor (VEGF) immunolabeling and the hyperglycaemic induced increase in ICAM