SS-208 Catalog No.:M26308-C Molecular basis of USP7 inhibition

Molecular basis of USP7 inhibition by selective small-molecule inhibitors

Smiles: CC1=CC(=CC=C1OC)S(=O)(=O)N1CCCCC1

which is followed by internucleosomal DNA fragmentation

Smiles: CC1(C)C[C@H]2[C@@]34C=C[C@@H]5[C@@]6(C)CC[C@H](O[C@@H]7O[C@H](C)[C@H](O)[C@H](O[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O)[C@H]7O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O)[C@@](C)(CO)[C@@H]6CC[C@@]5(C)[C@]3(C)C[C@H](O)[C@@]2(CO4)CC1

RAD51 Inhibitor B02 (B02) is an inhibitor of human RAD51 with an IC50 of 27

SS-208 Catalog No.:M26308-C Molecular basis of USP7 inhibitionSS 208 is a selective HDAC6 inhibitor, with an IC50 of 12 nM. SS 208 possesses anti tumor activity in melanoma. Product information CAS Number: 2245942 72 5 Molecular Weight: 344. 15 Formula: C13H11Cl2N3O4 Chemical Name: 5 {2 [(3,4 dichlorophenyl)formamido]ethyl} N hydroxy 1,2 oxazole 3 carboxamide Smiles: ONC(=O)C1C=C(CCNC(=O)C2=CC(Cl)=C(Cl)C=C2)ON=1 InChiKey: JFGOILLZIAIYGA UHFFFAOYSA N InChi: InChI=1S C13H11Cl2N3O4 c14 9 2 1 7(5 10(9)15)12(19)16 4