![TPA-023B )nitrosamine 6R)-3-(acetyloxy)-4-(dimethylamino)-6-methyloxan-2-yl]oxy}-12-{[(2R](https://cdn.shopify.com/s/files/1/0389/1897/9723/products/M26184_1635974217.gif?v=1635974218)
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6R)-3-(acetyloxy)-4-(dimethylamino)-6-methyloxan-2-yl]oxy}-12-{[(2R
6 µM using a recombinant KIX)
It inhibits hypoxia-inducible factor α (HIF-α) prolyl hydroxylase (HIF-PH)
1 μM of ON013100 results in an arrest of the G2/M phase of the cell cycle
5 mg/kg with i
TPA-023B )nitrosamine 6R)-3-(acetyloxy)-4-(dimethylamino)-6-methyloxan-2-yl]oxy}-12-{[(2RTPA 023B is a high affinity and orally active GABAA receptor 2 3 subtype (Kis of 0. 73 nM 2 nM) partial agonist and a 1 subtype (Ki of 1. 8 nM) antagonist. TPA 023B has non sedating anxiolytic like properties. Product information CAS Number: 425377 76 0 Molecular Weight: 391. 37 Formula: C21H15F2N5O Chemical Name: 2',6 difluoro 5' [3 (2 hydroxypropan 2 yl)imidazo[1,2 b][1,2,4]triazin 7 yl] [1,1' biphenyl] 2 carbonitrile Smiles:
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