Pay in 4 interest-free payments of $29.75 Learn more
Ships within 48 hours · Estimated delivery Jul 26 - Jul 31
Whereas lower doses of Cariprazine (0
48 hours) inhibits CK2-specific Akt phosphorylation
Smiles: CC(=O)O[C@@H]1C[C@@]2(C)[C@@H](CCC2=O)C2=C1[C@@]1(C)[C@@H](COC)OC(=O)C3=COC(=C13)C2=O
and appears to be well tolerated
PMID: 31619190
AC710 mesylate eridol D4 Whereas lower doses of CariprazineAC710 is a potent, orally active, and selective platelet derived growth factor receptor family kinase inhibitor with potential anticancer activity. Its IC50 values are 1. 2, 2, 7. 7 and 10. 5 nM for KIT, FLT3, PDGFR and CSF1R respectively; Kd = 1. 3 nM for PDGFR.. AC710 causes tumor regression of leukemia cell xenografts in mice. AC710 also reduces joint swelling and inflammation in a mouse model of collagen induced arthritis. AC710 is now a