Voruciclib l Enzalutamide D6 Smiles: C[C@H](O)[C@H](CC)N1N=CN(C1=O)C1=CC=C(C=C1)N1CCN(CC1)C1=CC=C(C=C1)OC[C@H]1C[C@@](CN2C=NC=N2)(OC1)C1=CC=C(F)C=C1F

Smiles: C[C@H](O)[C@H](CC)N1N=CN(C1=O)C1=CC=C(C=C1)N1CCN(CC1)C1=CC=C(C=C1)OC[C@H]1C[C@@](CN2C=NC=N2)(OC1)C1=CC=C(F)C=C1F

InChiKey: YYWGABLTRMRUIT-HWWQOWPSSA-N

4S)-3-hydroxy-4-[(2R

Gilteritinib inhibits the activity of eight of the 78 tested kinases by over 50% at concentrations of either 1 nM (FLT3

In a colorectal carcinoma (Colo205) xenograft study

Voruciclib l Enzalutamide D6 Smiles: C[C@H](O)[C@H](CC)N1N=CN(C1=O)C1=CC=C(C=C1)N1CCN(CC1)C1=CC=C(C=C1)OC[C@H]1C[C@@](CN2C=NC=N2)(OC1)C1=CC=C(F)C=C1FVoruciclib is an orally active and selective CDK inhibitor with Ki values of 0. 626 nM 9. 1 nM. Voruciclib potently blocks CDK9, the transcriptional regulator of MCL 1. Voruciclib represses expression of MCL 1 in multiple models of diffuse large B cell lymphoma (DLBCL). Product information CAS Number: 1000023 04 0 Molecular Weight: 469. 84 Formula: C22H19ClF3NO5 Chemical Name: 2 [2 chloro 4 (trifluoromethyl)phenyl] 5,7 dihydroxy 8 [(2R,3S) 2