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Average plasma Cmax values of tenapanor in rats and humans are less than 1 ng/mL with negligible area under the curve at doses of up to 30mg/kg in rats
The high levels of PARP expression confirmed the DNA breaks upon conjugate treatment
this agent accumulates in the cell cytoplasm where it inhibits protein kinase C (PKC)
single dose) reveals a high Cmax
A Gunia-Krzyżak
ML-099 20117 Average plasma Cmax values ofProduct information CAS Number: 496775 95 2 Molecular Weight: 259. 32 Formula: C14H13NO2S Chemical Name: 2 [(2 phenylethyl)sulfanyl]pyridine 3 carboxylic acid Smiles: OC(=O)C1=CC=CN=C1SCCC1C=CC=CC=1 InChiKey: UZERZZRWECLIKE UHFFFAOYSA N InChi: InChI=1S C14H13NO2S c16 14(17)12 7 4 9 15 13(12)18 10 8 11 5 2 1 3 6 11 h1 7,9H,8,10H2,(H,16,17) Technical Data Appearance: Solid Power Purity: 98% (or refer to the Certificate of Analysis) Shipping Condition:
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