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Thalidomide-NH-C8-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology
In DHER-14 cells
interfering with the cell's ability to process DNA
) reduces blood pressure to normotensive (< 120 mm Hg) levels without reflex tachycardia
Smiles: CC1C=C(O)C2=C3C=1C1C4=C(C(=O)C5C6=C(C7=C(C(C2=O)=C(O)C=C7O)C3=C64)C(O)=CC=5O)C(O)=CC=1C
Tubulysin C Catalog No.:M26102-C Thalidomide-NH-C8-NH2 hydrochloride is a synthesizedTubulysin C is a highly cytotoxic peptide isolated from the myxobacterial species Archangium geophyra and Angiococcus disciformis. Tubulysin displays extremely potent cytotoxic activity in mammalian cells, including multidrug resistant cell lines, with IC50 values in the lower nanomolar range. Tubulysin C is a cytotoxic activity tubulysin which inhibits tubulin polymerization and leads to cell cycle arrest and apoptosis. Product information CAS
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