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RQ-00203078 Catalog No.:M18441-C NGF ligand alters NGF signaling

SKU: 1586368594

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Description

NGF ligand alters NGF signaling via p75(NTR) and trkA

Stěpánek V

Ishihara K

InChi: InChI=1S/C8H16N2O4/c11-7(9-13)5-3-1-2-4-6-8(12)10-14/h13-14H

InChi: InChI=1S/C16H15FN2O4/c1-7-6-23-14-11(16(18)2-3-16)10(17)4-8-12(14)19(7)5-9(13(8)20)15(21)22/h4-5

RQ-00203078 Catalog No.:M18441-C NGF ligand alters NGF signalingRQ 00203078 is a highly selective, potent and orally active TRPM8 antagonist with IC50s of 5. 3 nM and 8. 3 nM for rat and human TRPM8 channels, respectively. RQ 00203078 shows little inhibitory action against TRPV1, TRPA1, TRPV4, or TRPM2 channels. Product information CAS Number: 1254205 52 1 Molecular Weight: 554. 85 Formula: C21H13ClF6N2O5S Chemical Name: 4 {[3 chloro 5 (trifluoromethyl)pyridin 2 yl]({[4

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