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CAS Number: 611207-11-5
2006 Mar 3
TAS-102 (Trifluridine-tipiracil hydrochloride mixture) and CPT-11 is a promising treatment option for colorectal or gastric cancer
and induces G2/M-phase growth arrest and cell death through the induction of apoptosis
InChiKey: NEHNMFOYXAPHSD-JTQLQIEISA-N
Endoxifen Z-isomer hydrochloride Size:Contact [email protected] for quotation CAS Number: 611207-11-5Endoxifen Z isomer hydrochloride is the most important Tamoxifen metabolite responsible for eliciting the anti estrogenic effects of this drug in breast cancer cells expressing estrogen receptor alpha (ER). Endoxifen inhibits hERG tail currents at 50 mV in a concentration dependent manner with IC50 values of 1. 6 M. IC50 value: 1. 6 M Target: hERG Potassium Channel, Estrogen Receptor ERREndoxifen is considered a prodrug, since it has a much higher
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