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SB-590885 is a more potent inhibitor than the previously described Raf/VEGFR kinase inhibitor BAY 439006 (Ki = 38 nM for mutant B-Raf
JNJ-26483327 (5 µM or 10 µM) with Herceptin treatment decreases HER2 phosphorylation in SKBR3 cells
Chemical Name: IKKgamma NBD Inhibitory Peptide
Blanchard RJ
2ClH/c1-36-24-18-22(19-25(37-2)28(24)40-5)30(34)42-16-8-12-32-10-7-11-33(15-14-32)13-9-17-43-31(35)23-20-26(38-3)29(41-6)27(21-23)39-4
IDO-IN-5 sin IM-1 SB-590885 is a more potentIDO IN 5 (NLG 1489) is an indoleamine 2,3 dioxygenase (IDO) inhibitor extracted from patent WO WO2012142237A1, compound 1489, has an IC50 of 1 10 M. Product information CAS Number: 1402837 79 9 Molecular Weight: 316. 37 Formula: C18H21FN2O2 Chemical Name: (1R,4r) 4 [(1R) 2 [(5R) 6 fluoro 5H imidazo[4,3 a]isoindol 5 yl] 1 hydroxyethyl]cyclohexan 1 ol Smiles: O[C@@H]1CC[C@H](CC1)[C@H](O)C[C@@H]1C2C(F)=CC=CC=2C2=CN=CN21 InChiKey: YGACXVRLDHEXKY
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