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InChiKey: LHIXVSSUGJJLKZ-VXKWHMMOSA-N
InChi: InChI=1S/C20H19NO5/c1-21-5-4-13-7-18-19(25-10-24-18)8-14(13)16(22)6-12-2-3-17-20(15(12)9-21)26-11-23-17/h2-3
GANT58 is a cell-permeable tetrapyridinylthiophene compound that acts as downstream Hedgehog (Hh) pathway blocker and targets Gli-mediated gene transactivation (IC50 ~ 5 µM in SAG-stimulated Shh-L2 cells)
and causes the activation of GSK-3β
S J O Keefe
Thalidomide-NH-PEG3-CH2CHO - CAS# 2360530-43-2 Catalog No.:M11569-2 InChiKey: LHIXVSSUGJJLKZ-VXKWHMMOSA-NThalidomide NH PEG3 CH2CHO is the Thalidomide based Cereblon ligand used in the recruitment of CRBN protein. Thalidomide NH PEG3 CH2CHO can be connected to the ligand for protein by a linker to form PROTAC BCL XL degrader XZ739 (HY 133557). Product information CAS Number: 2360530 43 2 Molecular Weight: 447. 44 Formula: C21H25N3O8 Chemical Name: 2 {2 [2 (2 {[2 (2, 6 dioxopiperidin 3 yl) 1, 3 dioxo 2, 3 dihydro 1H isoindol 4
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