![TPT-260 dihydrochloride - CAS# 2076-91-7 llardiine Smiles: CC1(C)O[C@@]2(C/C=C(/C)\C(O)=O)C(=O)[C@H]3C[C@@H]1[C@]12OC2=C(CC=C(C)C)C4O[C@](C)(CCC=C(C)C)C=CC=4C(O)=C2C(=O)C1=C3](https://cdn.shopify.com/s/files/1/0389/1897/9723/products/M9749_1621560737.gif?v=1742881892)
Pay in 4 interest-free payments of $26.77 Learn more
Ships within 48 hours · Estimated delivery Aug 6 - Aug 11
Smiles: CC1(C)O[C@@]2(C/C=C(/C)\C(O)=O)C(=O)[C@H]3C[C@@H]1[C@]12OC2=C(CC=C(C)C)C4O[C@](C)(CCC=C(C)C)C=CC=4C(O)=C2C(=O)C1=C3
is a potent and selective inhibitor of Bruton's tyrosine kinase (BTK)
Formula: C5H8N6Na2O5S
Int J Syst Evol Microbiol
SCHEMBL20844802
TPT-260 dihydrochloride - CAS# 2076-91-7 llardiine Smiles: CC1(C)O[C@@]2(C/C=C(/C)\C(O)=O)C(=O)[C@H]3C[C@@H]1[C@]12OC2=C(CC=C(C)C)C4O[C@](C)(CCC=C(C)C)C=CC=4C(O)=C2C(=O)C1=C3TPT 260 2HCl, also known as R55, is a thiophene thiourea derivative with molecule weight 260. 00 in free base form. There is no formal name yet, we temporally call this molecule as TPT 260. TPT260 acts as a chaperone to stabilize the retromer complex against thermal denaturation (Kd = ~ 5 M). In cultured hippocampal neurons, TPT 260 dose dependently increases the level of retromer proteins, redirects APP from the endosome, and reduces the formation of