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isolated from Nothapodytes foetida
ACY-957 is an orally active and selective inhibitor of HDAC1 and HDAC2
3-1(4)2(5)6/h8H
also known as DCC-270
WO 2018136700 A1 20180726
Losartan Carboxaldehyde 6681509 isolated from Nothapodytes foetidaLosartan is an inhibitor of endothelial cyclooxygenase (COX) 2. COX 2 produces prostaglandins that inhibit apoptosis and stimulate angiogenesis and invasiveness, and thus selective COX 2 inhibitors can reduce prostaglandin synthesis and restore apoptosis. In vitro: Losartan is an intermediate aldehyde metabolite of losartan, the angiotensin II type 1 receptor antagonist. Losartan could not block angiotensin receptors, but inhibit the expression of
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