Benazepril Hydrochloride 269970 produces a significant fall in

produces a significant fall in MBP

Rossignol JF

1423058-85-8

with an extrapolated geometric mean IC50 of approximately 20 mM resulting in a predicted selectivity index of 166

InChi: InChI=1S/C9H14N5O4P

Benazepril Hydrochloride 269970 produces a significant fall inBenazepril Hydrochloride is the hydrochloride salt of benazepril, a carboxyl containing angiotensin converting enzyme (ACE) inhibitor with antihypertensive activity. Benazeprilat competitively binds to and inhibits ACE, thereby blocking the conversion of angiotensin I to angiotensin II. This prevents the potent vasoconstrictive actions of angiotensin II, resulting in vasodilation. Benazeprilat also decreases angiotensin II induced aldosterone