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Chemical Name: N-(3-bromophenyl)-6
9 mg/kg per day for 14 days
PubMed Central PMCID: PMC4309183
6(9):e25093
Although the exact multiple mechanisms of action through which this agent exerts its effects have yet to be fully elucidated
ABT-888 dihydrochloride - CAS# 912445-05-7 0109 Chemical Name: N-(3-bromophenyl)-6ABT 888 dihydrochloride, also known asVeliparib, CAS No. 912445 05 7, is a potent and selective Poly (ADP Ribose) Polymerase (PARP) Inhibitor. ABT 888 dihydrochloride enhances apoptosis and autophagy in response to treatments that cause DNA breaks, including radiation and DNA alkylation. ABT 888 dihydrochloride is an orally bioavailable inhibitor of PARP1 and PARP2 (Kis = 5. 2 and 2. 9 nM, respectively). Product information CAS Number: 912445 05 7