Fingolimod hydrochloride 7903 ventilated OA-sensitive guinea pigs

ventilated OA-sensitive guinea pigs

CAS Number: 189232-42-6

67(2):83-92

InChi: InChI=1S/C20H21N7O3/c1-12-5-6-16(30-12)17-18-19(24-20(21)23-17)27(26-25-18)9-13-3-2-4-14(22-13)10-29-15-7-8-28-11-15/h2-6

2(6):799-803

Fingolimod hydrochloride 7903 ventilated OA-sensitive guinea pigsFingolimod hydrochloride (FTY720), an analog of sphingosine, is a potent sphingosine 1 phosphate (S1P) receptors modulator. Fingolimod hydrochloride is phosphorylated by sphingosine kinases, particularly by SK2, and then binds S1PR1, 3, 4, and 5. Fingolimod hydrochloride induces the internalization of S1P1, and consequently, inhibits S1P activity. Fingolimod hydrochloride also is a pak1 activator Product information CAS Number: 162359 56 0 Molecular