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SKF89976A hydrochloride is a selective GABA transporter (GAT-1) inhibitor with IC50s of 0
1 but not K2P4
Solubility: DMSO : 50 mg/mL (125
Formula: C18H16FN3O
3 μm and to potently induce differentiation as well as apoptosis
Muraglitazar dinitib-1 SKF89976A hydrochloride is a selectiveIC50: 0. 42 M: shows agonistic activity at peroxisome proliferator activated receptor (PPAR) IC50: 0. 14 M: shows agonistic activity at PPAR. Muraglitazar, a dual agonist of PPAR and PPAR, induces an increase in HDL C levels, a reduction of apolipoprotein B, total cholesterol, HbA1c and triglyceride. Muraglitazar is related to an increased risk of heart failure and adverse cardiovascular events. The PPARs, as a subfamily of the 48 member nuclear
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