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Int J Risk Saf Med
In the anesthetized guinea pigs
has minimum 32-fold selectivity against BRD9
and it causes selective ubiquitination and degradation of two lymphoid transcription factors
which is a classic anti-arrhythmic agent
Pixantrone (dimaleate) Catalog No.:M9764-10 Int J Risk Saf MedPixantrone is a synthetic, noncardiotoxic aza anthracenedione analogue with potential antineoplastic activity. Pixantrone intercalates into DNA and induces topoisomerase II mediated DNA strand crosslinks, resulting in inhibition of DNA replication and tumor cell cytotoxicity. Pixantrone is a potentially more effective, less cardiotoxic alternative to doxorubicin for patients with aggressive non Hodgkin lymphoma (aNHL). Product information CAS Number:
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