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8a-hexahydronaphthalen-1-yl (2S)-2-methylbutanoate
Pretreatment of adipocytes with GF-109203X (5 microM) reduced GSK-3 activity in total cell lysates
Smiles: CC1=CC(NC2N=CC(Cl)=C(NC3=CC=CC=C3S(=O)(=O)C(C)C)N=2)=C(C=C1C1CCNCC1)OC(C)C
JW55 functions via inhibition of the PARP domain of tankyrase 1 and tankyrase 2 (TNKS1/2)
Marešová H
Estramustine (phosphate sodium) eclizine dihydrochloride 8a-hexahydronaphthalen-1-yl (2S)-2-methylbutanoateEstramustine phosphate sodium is a synthetic molecule that combines estradiol and nornitrogen mustard through a carbamate link. Estramustine and its major metabolite estramustine bind to microtubule associated proteins (MAPs) and tubulin, thereby inhibiting microtubule dynamics and leading to anaphase arrest in a dose dependent fashion. This agent also exhibits anti androgenic effects. Check for active clinical trials or closed clinical trials using
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