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GSK923295 demonstrates broad efficacy against a panel of 19 human neuroblastoma derived cell lines with an average growth IC50 of 41 nM
2019 May 6
Teixeira MF
InChi: InChI=1S/C24H24N6O2S3/c31-19(15-17-7-3-1-4-8-17)25-23-29-27-21(34-23)11-13-33-14-12-22-28-30-24(35-22)26-20(32)16-18-9-5-2-6-10-18/h1-10H
is a potent inhibitor of embryonic ectoderm development protein (EED) and allosteric inhibitor of polycomb repressive complex 2 (PRC2)
Fluzoparib (SHR-3162) Size:10 mg solid GSK923295 demonstrates broad efficacy againstFluzoparib (SHR3162, HS10160) is a potent Poly (ADP ribose) polymerase (PARP) inhibitor that shows anti tumor activity. Product information CAS Number: 1358715 18 0 Molecular Weight: 472. 40 Formula: C22H16F4N6O2 Chemical Name: 4 (4 fluoro 3 (2 (trifluoromethyl) 5,6,7,8 tetrahydro [1,2,4]triazolo[1,5 a]pyrazine 7 carbonyl)benzyl)phthalazin 1(2H) one Smiles: O=C1NN=C(CC2C=C(C(F)=CC=2)C(=O)N2CC3=NC(=NN3CC2)C(F)(F)F)C2=CC=CC=C12 InChiKey: XJGXCBHXFWBOTN
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