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InChiKey: JRZJZOSWCNBQFS-UHFFFAOYSA-N
ClH/c1-2-3-4-5-6-10-17-25-22(24)20-13-15-21(16-14-20)23(26)27-18-19-11-8-7-9-12-19
p110α and p110β
with a kcat of 5
2013 May 24
BMS-1166 hydrochloride Catalog No.:M14627-2 InChiKey: JRZJZOSWCNBQFS-UHFFFAOYSA-NBMS 1166 hydrochloride is a potent PD 1 PD L1 immune checkpoint inhibitor. BMS 1166 hydrochloride induces dimerization of PD L1 and blocks its interaction with PD 1, with an IC50 of 1. 4 nM. BMS 1166 hydrochloride antagonizes the inhibitory effect of PD 1 PD L1 immune checkpoint on T cell activation. Product information CAS Number: 2113650 05 6 Molecular Weight: 677. 57 Formula: C36H34Cl2N2O7 Chemical Name: (2R,4R) 1 ({5 chloro 2 [(3
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