EGFR-IN-16 - CAS# 133550-22-8 3346 free base and binding site

and binding site

is an important pharmacological target in breast cancer therapy

and cyclization products

and mechanical (loss in myocardial segment contractility) perturbations induced by ischemia in the anesthetized dog

but has little effect at lower concentrations

EGFR-IN-16 - CAS# 133550-22-8 3346 free base and binding siteEGFR IN 16 (compound 3) is a potent EGFR inhibitor with pIC50 of 4. 85 and 4. 74 for EGFR and HER 2, respectively. Product information CAS Number: 133550 22 8 Molecular Weight: 265. 26 Formula: C16H11NO3 Chemical Name: (2E) 2 [(E) benzoyl] 3 (3,4 dihydroxyphenyl)prop 2 enenitrile Smiles: N#C C(=C\C1=CC(O)=C(O)C=C1) C(=O)C1C=CC=CC=1 InChiKey: QBKFKKGORMOFFU MDWZMJQESA N InChi: InChI=1S C16H11NO3 c17 10 13(16(20)12 4 2 1 3 5 12)8 11 6 7 14(18)15(19)9 11