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RO2959 hydrochloride(x) - CAS# 1219927-22-6 Catalog No.:M12941-2 6 Suppl 3:107-12

SKU: 9275026627

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Description

6 Suppl 3:107-12

InChiKey: QIKLOVZAPGSYNO-UHFFFAOYSA-N

ML-7 amplifies the quinocetone-induced cell death through akt and MAPK-mediated apoptosis on HepG2 cell line

Peroxisome proliferator-activated receptor-gamma1 is dephosphorylated and degraded during Bay11-7085-induced synovial fibroblast apoptosis

Chemical Name: 4-[[2-(2-Aminoethoxy)ethyl]amino]-2-(2

RO2959 hydrochloride(x) - CAS# 1219927-22-6 Catalog No.:M12941-2 6 Suppl 3:107-12RO2959 hydrochloride is a potent and selective CRAC channel inhibitor with an IC50 of 402 nM. RO2959 hydrochloride is a potent blocker of store operated calcium entry (SOCE) mediated by Orai1 Stim1 channels with an IC50 of 25 nM. RO2959 hydrochloride is also a potent inhibitor of human IL 2 production, and potently blocks T cell receptor triggered gene expression and T cell functional pathways. Product information CAS Number: 1219927 22 6 Molecular

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