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TRPC6 inhibitor l Estradiol 4-oxadiazole

SKU: 91803398714

4.7
USD150.00 USD194.00

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Description

4-oxadiazole

Y27632 (5 and 10 mg/kg) significantly prolongs the onset time of clonic convulsions when compare with saline group

InChiKey: URZFPFDMMGLCJC-AFGPOOCPSA-N

KRAS-C9 provides structure-based validation of a new allosteric regulatory site on Ras that is targetable in a mutant-specific manner

CAS Number: 500579-04-4

TRPC6 inhibitor l Estradiol 4-oxadiazoleSAR7334 is a novel, highly potent and bioavailable inhibitor of TRPC6 channels that opens new opportunities for the investigation of TRPC channel function in vivo. SAR7334 inhibited TRPC6, TRPC3 and TRPC7 mediated Ca(2+) influx into cells with IC50 s of 9. 5, 282 and 226 nM, whereas TRPC4 and TRPC5 mediated Ca(2+) entry was not affected. Product information CAS Number: 1333207 63 8 Molecular Weight: 440. 79 Formula: C21H24Cl3N3O Chemical Name: 4

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