Dasatinib Size:Solid 10 mg 2 nM for ERα degradation

2 nM for ERα degradation

Kitamura H

Smiles: CN1NC(=O)C(=O)N=C1SCC1CS[C@@H]2[C@H](NC(=O)/C(=N\OC)/C3=CSC(N)=N3)C(=O)N2C=1C(O)=O

is a small-molecule p75NTR modulator and proNGF antagonist

UK-383367 following incubation in rat plasma results in the half-life of 49 min

Dasatinib Size:Solid 10 mg 2 nM for ERα degradationDasatinib is a potent inhibitor of the non receptor tyrosine kinases Abl and Src as well as other members of the Src family. Dasatinib may have therapeutic value in fibrotic diseases characterized by elevated levels of Abl and Src kinases. Product information CAS Number: 302962 49 8 Molecular Weight: 488. 01 Formula: C22H26ClN7O2S Chemical Name: N (2 chloro 6 methylphenyl) 2 ({6 [4 (2 hydroxyethyl)piperazin 1 yl] 2 methylpyrimidin 4 yl}amino) 1,3