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and also greatly suppresses the stimulated IκB-α phosphorylation and degradation in HCECs
WO2020086963A1
InChi: InChI=1S/C36H62O31/c37-1-12-18(44)24(50)25(51)31(61-12)67-36(30(56)23(49)17(6-42)66-36)11-60-35(29(55)22(48)16(5-41)65-35)10-59-34(28(54)21(47)15(4-40)64-34)9-58-33(27(53)20(46)14(3-39)63-33)8-57-32(7-43)26(52)19(45)13(2-38)62-32/h12-31
Chemical Name: (3S)-3-(aminomethyl)-4-chloro-7-(2-hydroxyethoxy)-1
InChi: InChI=1S/C6H6N6O2/c1-11-6(14)12-2-8-3(4(7)13)5(12)9-10-11/h2H
Agomelatine-d4 - CAS# 1079389-44-8 Catalog No.:M34906-C and also greatly suppresses theAgomelatine d4 is the deuterium labeled Agomelatine. Agomelatine (S 20098) is a specific agonist of MT1 and MT2 receptors with Kis of 0. 1, 0. 06, 0. 12, and 0. 27 nM for CHO hMT1, HEK hMT1, CHO hMT2, and HEK hMT2, respectively. Agomelatine is a selective 5 HT2C receptor antagonist with pKis of 6. 4 and 6. 2 at native (porcine) and cloned, human 5 HT2C receptors, respectively. Product information CAS Number: 1079389 44 8 Molecular Weight: 247. 33
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