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S A Silbaugh
and the MICs varies depending on the source of the keratin
Smiles: NC1C=CN([C@H]2C[C@H](O)[C@@H](COP(=O)(OP(=O)(OP(=O)(OP(=O)(OC[C@H]3O[C@H]([C@H](O)[C@@H]3O)N3C=CC(=O)NC3=O)O[Na])O[Na])O[Na])O[Na])O2)C(=O)N=1
GNE-131 (Compound 13) shows moderate clearance in human liver microsomes and excellent functional activity against human NaV1
Chemical Name: 2-{[(3-{[2-(4-chlorophenyl)-5-methyl-1
PR5-LL-CM01 098rnicolide D S A SilbaughPR5 LL CM01 is a potent protein arginine methyltransferase 5 (PRMT5) inhibitor (IC50= 7. 5 M). Anti tumor activies. Product information CAS Number: 1005307 86 7 Molecular Weight: 401. 51 Formula: C23H27N7 Chemical Name: N6 [2 (dimethylamino)ethyl] N4 (3, 4 dimethylphenyl) 1 phenyl 1H pyrazolo[3, 4 d]pyrimidine 4, 6 diamine Smiles: CN(C)CCNC1N=C(NC2C=CC(C)=C(C)C=2)C2C=NN(C3C=CC=CC=3)C=2N=1 InChiKey: UPAZOMJFUXPAJI UHFFFAOYSA N InChi: InChI=1S C23H27N7