WS6 - β Cell Proliferation Inducer. CAS# 1421227-53-3 Catalog No.:M60097-2S Treatment of MCL cell lines

Treatment of MCL cell lines with EPZ015666 led to inhibition of SmD3 methylation and cell death

PubMed Central PMCID: PMC5007443

CAS Number: 1374516-07-0

17(22):7116-26

resulting in the proteasomal degradation of oncogenic client proteins

WS6 - β Cell Proliferation Inducer. CAS# 1421227-53-3 Catalog No.:M60097-2S Treatment of MCL cell linesWS6, CAS No. 1421227 53 3, is a highly potent and selective small molecule that promotes pancreatic cell proliferation in rodent and human primary islets, identified by a high throughput, cell based screening using rodent pancreatic cells. It can induce proliferation of mouse R7T1 cells with an EC50 ~0. 28 M, and induce up to 4% of rat cells and 3% of human cells to proliferate, with a similar EC50 of 0. 4 M. WS6 induces proliferation of primary rat