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Binding affinities (Ki) of OBE022 for the human and rat FP receptor are 1 nM and 26 nM respectively
Daily exposure of PD-166866 to L6 cells at concentrations from 1 to 100 nM results in a concentration-related inhibition of bFGF-stimulated cell growth for 8 consecutive days with an IC50 value of 24 nM
Formula: C6H14BrNO3
InChi: InChI=1S/C25H16FN3O3/c1-13-10-16(12-29-23(13)26)14-6-8-15(9-7-14)20-18(11-27)24(28)32-22-17-4-2-3-5-19(17)31-25(30)21(20)22/h2-10
Both receptors can negatively regulate adenylate cyclase and control the release of arachidonic acid
Mal-PEG2-VCP-NB arotene-d8 Binding affinities (Ki) of OBE022Mal PEG2 VCP NB is a claevable ADC linker containing a Maleimide group, 2 unit PEG and a VCP NB. Product information CAS Number: 2395887 69 9 Molecular Weight: 783. 78 Formula: C36H45N7O13 Chemical Name: {4 [(2S) 5 (carbamoylamino) 2 [(2S) 2 (3 {2 [2 (2,5 dioxo 2,5 dihydro 1H pyrrol 1 yl)ethoxy]ethoxy}propanamido) 3 methylbutanamido]pentanamido]phenyl}methyl 4 nitrophenyl carbonate Smiles:
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