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LY315920(Varespladib) endizoate C[C@@H](CC)[C@H](N)C(=O)NCCN1CCOCC1

SKU: 88483252402

4.2
USD100.00 USD145.00

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Description

C[C@@H](CC)[C@H](N)C(=O)NCCN1CCOCC1

is an oral active and potent CRTh2 receptor antagonist and potentially useful for asthma treatment

potent and cell-permeable inhibitor of p38 MAP kinase

Negative control for VH 298

Formula: C17H15NO2

LY315920(Varespladib) endizoate C[C@@H](CC)[C@H](N)C(=O)NCCN1CCOCC1Varespladib, aslo known as LY315920, is a secreted phospholipase A2 (sPLA2) inhibitor (IC50 = 50 750 nM for a range of sPLA2 isoforms). Varespladib reduces atherosclerosis and aneurysm formation in ApoE mice and in guinea pigs. Varespladib significantly reduces the post ACS inflammatory response in those with and without diabetes. Varespladib may be potentially useful for treatment of coronary artery disease. Product information CAS Number: 172732 68

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