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Ro 46-8443 is the first non-peptide Endothelin Receptor B selective antagonist with IC50 value of 110nM
Preclinical studies indicate that LX7101 significantly reduced intraocular pressure in both mouse and monkey models
ClH/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24
Nepafenac D5 (AHR-9434 D5) is the deuterium labeled Nepafenac
1246529-32-7
SR-3306 HA-665752 Ro 46-8443 is the firstSR 3306 is an aminopyrimidine JNK inhibitor. SR 3306 reduces the loss of dopaminergic cell bodies in the SNpc and their terminals in the striatum produced by unilateral injection of 6 hydroxydopamine (6 OHDA) into the nigrostriatal pathway. Product information CAS Number: 1128096 91 2 Molecular Weight: 490. 56 Formula: C28H26N8O Chemical Name: N {4 [3 (6 methylpyridin 3 yl) 1H 1,2,4 triazol 1 yl]phenyl} 4 [3 (morpholin 4 yl)phenyl]pyrimidin 2 amine
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