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Ferrer-Torres D
and shows selectivity over a panel of other bromodomains
NVP-TNKS656 was dosed to mice orally to stabilize Axin1 protein and reduce the Wnt/beta-catenin target gene Axin2 mRNA level by 70-80%
InChiKey: WCKZRLOUKYFJDY-UHFFFAOYSA-N
4 hours) inhibits STAT1 phosphorylation without causing JAK1/2 degradation
WAY-600 ebutine maleate Ferrer-Torres DWAY 600 is a potent, ATP competitive and selective inhibitor of mTOR with IC50 of 9 nM. Product information CAS Number: 1062159 35 6 Molecular Weight: 494. 59 Formula: C28H30N8O Chemical Name: 4 (6 (1H indol 5 yl) 1 (1 (pyridin 3 ylmethyl)piperidin 4 yl) 1H pyrazolo[3, 4 d]pyrimidin 4 yl)morpholine Smiles: C(C1=CN=CC=C1)N1CCC(CC1)N1N=CC2C1=NC(=NC=2N1CCOCC1)C1C=C2C=CNC2=CC=1 InChiKey: FPEIJQLXFHKLJV UHFFFAOYSA N InChi: InChI=1S C28H30N8O c1 2 20(17 29