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and that Z-360 combined with gemcitabine prolonged survival in a pancreatic carcinoma orthotopic xenograft mice
VPC-14337 decreases messenger RNA (mRNA) and protein levels of known WNT target genes as c-MYC and thereby led to the induction of p21
NK-252 displays this effect with higher potency than OPZ based on the fact that the EC2 value (concentration for a 2-fold induction above background)
Solubility: DMSO : ≥ 125 mg/mL (304
1515/jpm-2018-0010
endo-BCN-PEG3-NHS ester Catalog No.:M28608-C and that Z-360 combined withendo BCN PEG3 NHS ester is a PEG based PROTAC linker that can be used in the synthesis of PROTACs. Product information CAS Number: 2101206 94 2 Molecular Weight: 494. 53 Formula: C24H34N2O9 Chemical Name: 2,5 dioxopyrrolidin 1 yl 3 {2 [2 (2 {[({bicyclo[6. 1. 0]non 4 yn 9 yl}methoxy)carbonyl]amino}ethoxy)ethoxy]ethoxy}propanoate Smiles: O=C(NCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O)OCC1C2CCC#CCCC21 InChiKey: HCELGENRAWFQSJ UHFFFAOYSA N InChi: InChI=1S C24H34N2O9
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