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InChiKey: SWLMUYACZKCSHZ-UHFFFAOYSA-N
Formula: C33H37N3O13
Formula: C25H26N2O5
InChi: InChI=1S/C20H24N10O13P2/c21-14-8-15(24-3-23-14)29(4-25-8)18-10(31)12-6(40-18)1-38-45(36
Momin RA et al
AES-350 - CAS# 847249-57-4 12841 InChiKey: SWLMUYACZKCSHZ-UHFFFAOYSA-NAES 350 is a potent and orally active HDAC6 inhibitor with an IC50 and a Ki of 0. 0244 M and 0. 035 M, respectively. AES 350 is also against HDAC 3, 8, and 11 in an enzymatic activity assay with IC50 values of 0. 187 M, 0. 245 M, and >1M, respectively. AES 350 triggers apoptosis in AML cells through HDAC inhibition and can be used for acute myeloid leukemia (AML) research. Product information CAS Number: 847249 57 4 Molecular Weight: 312. 36 Formula:
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