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Dicyclomine hydrochloride Catalog No.:M29971-C Arctigenin is a lignan found

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Description

Arctigenin is a lignan found in certain plants of the Asteraceae

InChiKey: TUNUVJALSUOKOC-VPJFHDDISA-N

CN([C@H](CN1CCCC1)C1C=C(C=CC=1)OCC(O)=O)C(=O)CC1C=C(Cl)C(Cl)=CC=1

with an extrapolated geometric mean IC50 of approximately 20 mM resulting in a predicted selectivity index of 166

3H2O/c2*1-23-13-5-6-19-12(14(13)24-2)8-26(22)16-20-10-4-3-9(25-15(17)18)7-11(10)21-16

Dicyclomine hydrochloride Catalog No.:M29971-C Arctigenin is a lignan foundDicyclomine hydrochloride is a potent and orally active muscarinic cholinergic receptors antagonist. Dicyclomine hydrochloride shows high affinity for muscarinic M1 receptor subtype (Ki=5. 1 nM) and M2 receptor subtype (Ki=54. 6 nM) in brush border membrane and basal plasma membranes, respectively. Dicyclomine is an antispasmodic agent and relieves smooth muscle spasm of the gastrointestinal tract in vivo. Product information CAS Number: 67 92 5

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