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RGFP966 was used at 10 µM final concentration in various in vitro assays
RK-33 impairs radiation-induced DNA damage repair by inhibiting NHEJ activity
Nutlin-3 can block the MDMX–p53 interaction and induce the p53 pathway in retinoblastoma cells (Weri1) with IC50 of 0
33 mg/mL (228
InChiKey: VXNYQUQHOUERTR-UHFFFAOYSA-N
Dasatinib monohydrate - CAS# 863127-77-9 isandrin C RGFP966 was used at 10Dasatinib (BMS 354825) monohydrate is a highly potent, ATP competitive, orally active dual Src Bcr Abl inhibitor with potent antitumor activity. The Kis are 16 pM and 30 pM for Src and Bcr Abl, respectively. Dasatinib monohydrate inhibits Bcr Abl and Src with IC50s of <1. 0 nM and 0. 5 nM, respectively. Dasatinib monohydrate also induces apoptosis and autophagy. Product information CAS Number: 863127 77 9 Molecular Weight: 506. 02 Formula:
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