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HDAC inhibitor SAHA
69(7):1649-1661
manifesting similar oral and subcutaneous exposure in mice
192(7):3383-9
Solubility: DMSO up to 15 mM
TBA-354 Catalog No.:M8471-2 HDAC inhibitor SAHATBA 354, also known as SN31354, is a potent anti tuberculosis drug candidate. TBA 354 is narrow spectrum and bactericidal in vitro against replicating and nonreplicating Mycobacterium tuberculosis, with potency similar to that of delamanid and greater than that of PA 824. TBA 354 maintains activity against Mycobacterium tuberculosis H37Rv isogenic monoresistant strains and clinical drug sensitive and drug resistant isolates. TBA 354 is a promising
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