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InChi: InChI=1S/C10H12O4/c1-13-8-4-3-7(6-10(11)12)5-9(8)14-2/h3-5H
Smiles: O/C(/NC1C=CC(=CC=1)C1=CC=NC=C1)=N\[C@H](CO)C1C=CC=CC=1
KRAS-BRAF interaction
When combined with a 1 mg/kg dose of N-Arachidonyl maleimide
doxorubicin (210-fold)
ALK-IN-9 inostat InChi: InChI=1S/C10H12O4/c1-13-8-4-3-7(6-10(11)12)5-9(8)14-2/h3-5HALK IN 9 (compound 40) is a potent ALK inhibitor. ALK IN 9 inhibits cell proliferation with IC50s of <0. 2 nM, <0. 2 nM, 0. 2 nM for Ba F3 EML4 ALK, KM 12 (TPM3 TRKA), KG l cell (OP2 FGFR1), respectively. Product information CAS Number: 2359662 39 6 Molecular Weight: 412. 42 Formula: C20H21FN6O3 Chemical Name: (18R) 13 fluoro 7,7,18 trimethyl 9,20 dioxa 1,2,6,11,17,23 hexaazapentacyclo[19. 3. 1. 0,. 0,. 0,]pentacosa 2,4(24),10,12,14,21(25),22 heptaen