![Sphingosine-1-phosphate ngin (Naringoside) Chemical Name: N-{3-[(5-chloro-2-{[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)oxy]phenyl}propanamide](https://cdn.shopify.com/s/files/1/0389/1897/9723/files/1686201573322.png?v=1686201622)
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Chemical Name: N-{3-[(5-chloro-2-{[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)oxy]phenyl}propanamide
Solubility: H2O : 25 mg/mL (19
Formula: C22H17N3O2
which inhibits CFTR with an IC50 of 8 nM
BMS-345541 (10 μM) inhibits growth of Normal human epidermal melanocytes
Sphingosine-1-phosphate ngin (Naringoside) Chemical Name: N-{3-[(5-chloro-2-{[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)oxy]phenyl}propanamideSphingosine 1 phosphate (S1P) is an agonist of S1P1 5 receptors and a ligand of GPR3, GPR6 and GPR12. Sphingosine 1 phosphate is an intracellular second messenger and mobilizes Ca2+ as an extracellular ligand for G protein coupled receptors. Sphingosine 1 phosphate is an important lipid mediator generated from Sphingomyelin (HY 113498) or other membrane phospholipids. Product information CAS Number: 26993 30 6 Molecular Weight: 379. 47 Formula:
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