(S)-Willardiine Catalog No.:M8448-2 IC50 value:Target:Astragaloside II and isoastragaloside

IC50 value:Target:Astragaloside II and isoastragaloside I selectively increased adiponectin secretion in primary adipocytes without any obvious effects on a panel of other adipokines

Smiles: CC1C[C@@]2(N)/C(=C\C)/[C@H](CC3NC(=O)C=CC2=3)C=1

pharmthera

Chemical Name: (S)-N-(4-((2S

NB-598 suppresses triglyceride biosynthesis through the farnesol pathway

(S)-Willardiine Catalog No.:M8448-2 IC50 value:Target:Astragaloside II and isoastragaloside(S) Willardiine is a potent agonist of AMPA kainate receptors with EC50 of 44. 8 uM. IC50 value: 44. 8 uM(EC50) Target: AMPA kainate receptor agonistin vitro: The (S) but not (R) isomers of willardiine and 5 bromowillardiine were potent agonists, producing rapidly but incompletely desensitizing responses . At a concentration of 1. 8 mM, Ca2+ inhibited the currents induced by 100 microM willardiine by approximately 50% . in vivo: In newborn mice (P5,