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BLK-IN-2 Size:Contact [email protected] for quotation Smiles: OC(CN1C2=CC=C(Cl)C=C2C2=CC(Cl)=CC=C12)CN1C(=O)SCC1=O

SKU: 75846022656

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Description

Smiles: OC(CN1C2=CC=C(Cl)C=C2C2=CC(Cl)=CC=C12)CN1C(=O)SCC1=O

25-Hydroxy vitamin D3 modulates dendritic cell phenotype and function in Crohn's disease

causing the cleavage of caspase-3 and caspase-7

InChiKey: VJIVKRQGSGBLFP-UHFFFAOYSA-N

3-²H₆)propan-2-yl]amino}-1-[4-hydroxy-3-(hydroxymethyl)phenyl]ethan-1-one hydrochloride

BLK-IN-2 Size:Contact [email protected] for quotation Smiles: OC(CN1C2=CC=C(Cl)C=C2C2=CC(Cl)=CC=C12)CN1C(=O)SCC1=OBLK IN 2 (compound 25) is a potent and selective irreversible inhibitor of B Lymphoid tyrosine kinase (BLK), with an IC50 of 5. 9 nM. BLK IN 2 also inhibits BTK (IC50=202. 0 nM). BLK IN 2 shows potent antiproliferative activities against several lymphoma cells. Product information CAS Number: 2694871 86 6 Molecular Weight: 683. 80 Formula: C39H41N9O3 Smiles: CN(C)C C=C

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