Tyrphostin B44, (-) enantiomer 13465 [2H]C([C@](CCCN(C)CCC1C=CC(OC)=C(C=1)OC)(C#N)C1=CC(OC)=C(C=C1)OC)(C([2H])([2H])[2H])C([2H])([2H])[2H]

[2H]C([C@](CCCN(C)CCC1C=CC(OC)=C(C=1)OC)(C#N)C1=CC(OC)=C(C=C1)OC)(C([2H])([2H])[2H])C([2H])([2H])[2H]

GI254023x also prevents CXCL16 shedding from the cell membrane and is even more potent than TAPI-2

with good aqueous solubility

a panel of human tumor cell lines is treated in vitro at various concentrations of inhibitor

(2014) Chem Biol

Tyrphostin B44, (-) enantiomer 13465 [2H]C([C@](CCCN(C)CCC1C=CC(OC)=C(C=1)OC)(C#N)C1=CC(OC)=C(C=C1)OC)(C([2H])([2H])[2H])C([2H])([2H])[2H]Product information CAS Number: 133550 32 0 Molecular Weight: 308. 33 Formula: C18H16N2O3 Chemical Name: (2E) 2 cyano 3 (3,4 dihydroxyphenyl) N [(1R) 1 phenylethyl]prop 2 enamide Smiles: C[C@@H](NC(=O) C(=C C1=CC(O)=C(O)C=C1) C#N)C1C=CC=CC=1 InChiKey: UMGQVUWXNOJOSJ KMHUVPDISA N InChi: InChI=1S C18H16N2O3 c1 12(14 5 3 2 4 6 14)20 18(23)15(11 19)9 13 7 8 16(21)17(22)10 13 h2 10,12,21 22H,1H3,(H,20,23) b15 9+ t12 m1 s1 Technical Data Appearance: Solid