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5-a]pyrimidin-3-yl}quinoline hydrochloride
Formula: C22H29FO5
Cytotoxic activity of the MK2 inhibitor CMPD1 in glioblastoma cells is independent of MK2
also known as SJB 019
CAS Number: 2468780-87-0
3-(4-Pyridyl)indole Catalog No.:M22402-C 5-a]pyrimidin-3-yl}quinoline hydrochloride3 (4 pyridyl)indole (Rockout) is a Rho kinase inhibitor . Rho associated protein kinase (ROCK) belongs to a family of serine threonine kinases mainly involved in regulating the shape and movement of cells by acting on the cytoskeleton . Rockout caused decreased migration and aberrant morphology. Rockout showed no effect on phagocytosis, listeria motility or actin polymerization in permeabilized yeast. In a human melanoma cell line M2 cells that blebs
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