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InChi: InChI=1S/C25H37FN8O2/c1-15-12-33(16(2)11-32(15)13-18-6-8-36-9-7-18)24(35)34-14-19-21(25(34
FH535 inhibits recruitment of the coactivators GRIP1 and β-catenin to PPARδ and PPARγ
Sundararaman P
(R)-(1-(2-(2
Smiles: CC1(C)CC[C@H](O)[C@@]2(C)[C@H]1[C@H](O)[C@H](OC(C)=O)[C@@]1(C)O[C@](C)(CC(=O)[C@@]12O)C=C
GS967 ibitor VIII InChi: InChI=1S/C25H37FN8O2/c1-15-12-33(16(2)11-32(15)13-18-6-8-36-9-7-18)24(35)34-14-19-21(25(34GS967, also known as GS 458967, is a highly selective late sodium channel current blocker. The selective inhibition of late INa with GS967 can exert antiarrhythmic effects by suppressing EAD and DAD mediated extrasystolic activity in PFs and PV and SVC sleeve preparations. Selective late INa inhibition with GS967 exerts potent protective effects against ischemia induced depolarization and repolarization abnormalities in both atria and ventricles.
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