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18)38)43-28-24(23(35)22(34)20(11-30)41-28)42-26(37)21-16(9-15(32)10-19(21)33)13-4-3-5-14(31)8-13/h2-5
2014 Mar 13
25-200 μM) does not exhibit any cytotoxic effect
and SRB12 cells)
Chemical Name: 3-[3-(hydroxymethyl)-2
Tat-beclin 1 TFA 15009 18)38)43-28-24(23(35)22(34)20(11-30)41-28)42-26(37)21-16(9-15(32)10-19(21)33)13-4-3-5-14(31)8-13/h2-5Tat beclin 1 TFA, a peptide derived from a region of the autophagy protein (beclin 1), is a potent inducer of autophagy and interacts with negative regulator of autophagy, GAPR 1 (GLIPR2). Tat beclin 1 TFA decreases the accumulation of polyglutamine expansion protein aggregates and the replication of several pathogens (including HIV 1) in vitro, and reduces mortality in mice infected with chikungunya (CHIKV) or West Nile virus (WNV). Product
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